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Article

Prevalence of resistance-associated substitutions (RAS) in hepatitis C virus in the Former Soviet Union countries.

BMJ open gastroenterology - 23 Jan 2025

Mustafa Aidana, Davlidova Salima, Abidi Syed Hani, Begimbetova Dinara, Heimer Robert, Vermund Sten H, Ali Syed

Abstract excerpt

OBJECTIVE: The emergence of resistance-associated substitutions (RASs) poses a significant challenge to the effective treatment of hepatitis C virus (HCV) infection using direct-acting antivirals. This study's objective was to observe the prevalence of HCV genotypes and RAS within the Former Soviet Union (FSU) countries. METHODS: We analysed 60 NS3, 313 NS5A and 1119 NS5B sequences of HCV deposited in open-access...

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Identifiers

PMID: 39848793
DOI: 10.1136/bmjgast-2024-001657
PMCID: PMC11758705

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