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Article

Can Non-HLA Single Nucleotide Polymorphisms Help Stratify Risk in TrialNet Relatives at Risk for Type 1 Diabetes?

The Journal of clinical endocrinology and metabolism - 1 Aug 2017

Steck Andrea K, Xu Ping, Geyer Susan, Redondo Maria J, Antinozzi Peter, Wentworth John M, Sosenko Jay, Onengut-Gumuscu Suna, Chen Wei-Min, Rich Stephen S, Pugliese Alberto

Abstract excerpt

Context: Genome-wide association studies identified >50 type 1 diabetes (T1D) associated non-human leukocyte antigens (non-HLA) loci. Objective: The purpose of this study was to assess the contribution of non-HLA single nucleotide polymorphisms (SNPs) to risk of disease progression. Design and Setting: The TrialNet Pathway to Prevention Study follows relatives of T1D patients for development of autoantibodies...

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Identifiers

PMID: 28520980
DOI: 10.1210/jc.2016-4003
PMCID: PMC5546868

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GLIS3
CCR7

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