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Article

Cross-sex transplantation alters gene expression and enhances inflammatory response in the transplanted kidneys.

American journal of physiology. Renal physiology - 1 Aug 2017

Wang Lei, Song Jiangping, Wang Shaohui, Buggs Jacentha, Chen Rongjun, Zhang Jie, Wang Liqing, Rong Song, Li Wenbin, Wei Jin, Liu Ruisheng

Abstract excerpt

Kidney transplantation (KTX) is a life-saving procedure for patients with end-stage renal disease. Expression levels of many genes in the kidney vary between males and females, which may play an essential role in the sex differences in graft function. However, whether these differences are affected after cross-sex-KTX is unknown. In the present study, we assessed postoperative changes in genotype, function, and...

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Identifiers

PMID: 28515172
DOI: 10.1152/ajprenal.00039.2017
PMCID: PMC5582902

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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