Article
Role of the transcription factor erythroblastosis virus E26 oncogen homolog-1 (ETS-1) as mediator of the renal proinflammatory and profibrotic effects of angiotensin II.
Hypertension (Dallas, Tex. : 1979) - 1 Nov 2012
Feng Wenguang, Chumley Phillip, Hua Ping, Rezonzew Gabriel, Jaimes David, Duckworth Madison W, Xing Dongqi, Jaimes Edgar A
Abstract excerpt
Angiotensin II (Ang II) plays a major role in the pathogenesis of end-organ injury in hypertension via its diverse hemodynamic and nonhemodynamic effects. Erythroblastosis virus E26 oncogen homolog-1 (ETS-1) is an important transcription factor recently recognized as an important mediator of cell proliferation, inflammation, and fibrosis. In the present studies, we tested the hypothesis that ETS-1 is a common...
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