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Article

Sibling method increases risk assessment estimates for type 1 diabetes.

PloS one - 1 Jan 2017

Lam Hoang V, Nguyen Dat T, Nguyen Cao D

Abstract excerpt

We presented a risk assessment model to distinguish between type 1 diabetes (T1D) affected and unaffected siblings using only three single nucleotide polymorphism (SNP) genotypes. In addition we calculated the heritability from genome-wide identity-by-descent (IBD) sharing between full siblings. We analyzed 1,253 pairs of affected individuals and their unaffected siblings (750 pairs from a discovery set and 503...

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Identifiers

PMID: 28510587
DOI: 10.1371/journal.pone.0176341
PMCID: PMC5433695

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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