Article

Effects of parental autoimmune diseases on type 1 diabetes in offspring can be partially explained by HLA and non-HLA polymorphisms

2024-04-19

Abstract excerpt

<h4>SUMMARY</h4> Type 1 diabetes (T1D) and other autoimmune diseases (AIDs) often co-occur in families. Leveraging data from 58,284 family trios in Finnish nationwide registers (FinRegistry), we identified that, out of 50 parental AIDs examined, 15 were associated with an increased T1D risk in offspring. These identified epidemiological associations were further assessed in 470K genotyped Finns from FinnGen study...

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Literature Corpus work: 980e99de-71e2-5703-ae7b-3e7b365b15a0
DOI: 10.1101/2024.04.16.24305884

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