Article
A continuum of genetic liability for minor and major depression.
Translational psychiatry - 16 May 2017
Corfield E C, Yang Y, Martin N G, Nyholt D R
Abstract excerpt
The recent success of a large genome-wide association (GWA) study-analysing 130 620 major depression cases and 347 620 controls-in identifying the first single-nucleotide polymorphism (SNP) loci robustly associated with major depression in Europeans confirms that immense sample sizes are required to identify risk loci for depression. Given the phenotypic similarity between major depressive disorder (MDD) and the...
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