Article
Variation in the region of the angiotensin-converting enzyme gene influences interindividual differences in blood pressure levels in young white males.
Circulation - 12 May 1998
Fornage M, Amos C I, Kardia S, Sing C F, Turner S T, Boerwinkle E
Abstract excerpt
BACKGROUND: The renin-angiotensin system regulates blood pressure through its effects on vascular tone, renal hemodynamics, and renal sodium and fluid balance. METHODS AND RESULTS: Using data from a large population-based sample of 1488 siblings having a mean age of 14.8 years and belonging to th...
Topics
- Adolescent
- Angiotensinogen
- Blood Pressure
- Cardiovascular Diseases
- Cohort Studies
- Diastole
- Disease Susceptibility
- Genetic Linkage
- Genetic Variation
- Genotype
- Humans
- Hypertension
- Male
- Microsatellite Repeats
- Minnesota
- Nuclear Family
- Peptidyl-Dipeptidase A
- Receptor, Angiotensin, Type 1