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Article

Variation in the region of the angiotensin-converting enzyme gene influences interindividual differences in blood pressure levels in young white males.

Circulation - 12 May 1998

Fornage M, Amos C I, Kardia S, Sing C F, Turner S T, Boerwinkle E

Abstract excerpt

BACKGROUND: The renin-angiotensin system regulates blood pressure through its effects on vascular tone, renal hemodynamics, and renal sodium and fluid balance. METHODS AND RESULTS: Using data from a large population-based sample of 1488 siblings having a mean age of 14.8 years and belonging to the youngest generation of 583 randomly ascertained three-generation pedigrees from Rochester, Minn, we carried out...

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Source

Identifiers

PMID: 9603530
DOI: 10.1161/01.cir.97.18.1773

Genes

ACE
DBP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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