Article
Population-based sample reveals gene-gender interactions in blood pressure in White Americans.
Hypertension (Dallas, Tex. : 1979) - 1 Jan 2007
Rana Brinda K, Insel Paul A, Payne Samuel H, Abel Kenneth, Beutler Ernest, Ziegler Michael G, Schork Nicholas J, O'Connor Daniel T
Abstract excerpt
The influence of genetic contributors, such as common single nucleotide polymorphisms, on blood pressure and essential hypertension may vary with the gender. We used the power of a large, community-based sample to probe whether gender interacts with genes in contributing to extremes of blood pressure in 611 male and 656 female age-matched white Americans within the top and bottom 5th percentiles of blood pressure...
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