Article
RXRB Is an MHC-Encoded Susceptibility Gene Associated with Anti-Topoisomerase I Antibody-Positive Systemic Sclerosis.
The Journal of investigative dermatology - 1 Sept 2017
Oka Akira, Asano Yoshihide, Hasegawa Minoru, Fujimoto Manabu, Ishikawa Osamu, Kuwana Masataka, Kawaguchi Yasushi, Yamamoto Toshiyuki, Takahashi Hiroki, Goto Daisuke, Endo Hirahito, Jinnin Masatoshi, Mano Shuhei, Hosomichi Kazuyoshi, Mabuchi Tomotaka, Ueda Mahoko Takahashi, Nakagawa So, Beck Stephan, Bahram Seiamak, Takehara Kazuhiko, Sato Shinichi, Ihn Hironobu
Abstract excerpt
Systemic sclerosis is a systemic autoimmune and connective tissue disorder associated with the human leukocyte antigen locus. However, the functional relationship between human leukocyte antigen gene(s) and disease development remains unknown. To elucidate major histocompatibility complex-linked systemic sclerosis genetics, we performed genotyping of major histocompatibility complex-borne microsatellites and...
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