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Article

RACK-1, a multifaceted regulator is required for C. elegans innate immunity against S. flexneri M9OT infection.

Developmental and comparative immunology - 1 Sept 2017

Marudhupandiyan Shanmugam, Prithika Udayakumar, Balasubramaniam Boopathi, Balamurugan Krishnaswamy

Abstract excerpt

The nematode C. elegans has the ability to clear off bacterial colonization in the intestine using pathogen specific innate immune response. Here, we show that C. elegans RACK-1 has been vital in determining the survival of worms under specific pathogenic infection. Among various pathogens tested, S. flexneri M9OT (SF) exhibited highest pathogenicity by killing rack-1 mutant worm-VC3013 earlier when compared to...

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Share to Caenorhabditis elegans Proteins
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 28502651
DOI: 10.1016/j.dci.2017.05.008

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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