Article
Caenorhabditis elegans-based screen identifies Salmonella virulence factors required for conserved host-pathogen interactions.
Current biology : CB - 8 Jun 2004
Tenor Jennifer L, McCormick Beth A, Ausubel Frederick M, Aballay Alejandro
Abstract excerpt
A Caenorhabditis elegans-Salmonella enterica host-pathogen model was used to identify both novel and previously known S. enterica virulence factors (HilA, HilD, InvH, SptP, RhuM, Spi4-F, PipA, VsdA, RepC, Sb25, RfaL, GmhA, LeuO, CstA, and RecC), including several related to the type III secretion system (TTSS) encoded in Salmonella pathogenicity island 1 (SPI-1). Mutants corresponding to presumptive novel...
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