Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Caenorhabditis elegans mom-4 is required for the activation of the p38 MAPK signaling pathway in the response to Pseudomonas aeruginosa infection.

Protein & cell - 1 Jan 2013

Xu Ajing, Shi Guojun, Liu Feng, Ge Baoxue

Abstract excerpt

The p38 mitogen-activated protein kinase (MAPK) plays an evolutionarily conserved role in the cellular response to microbial infection and environmental stress. Activation of p38 is mediated through phosphorylation by upstream MAPKK, which in turn is activated by MAPKKK. In the Caenorhabditis elegans, the p38 MAPK (also called PMK-1) signaling pathway has been shown to be required in its resistance to bacterial...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Caenorhabditis elegans
Share to Caenorhabditis elegans Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Disease Resistance

Share to MAP Kinase Kinase 1

Share to MAP Kinase Signaling System

Share to p38 Mitogen-Activated Protein Kinases

Share to Pseudomonas aeruginosa

Share to Pseudomonas Infections

Source

Open in PubMed Open full text

Identifiers

PMID: 23212155
DOI: 10.1007/s13238-012-2080-z
PMCID: PMC4875442

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Caenorhabditis elegans mom-4 is required for the activation of the p38 MAPK signaling pathway in the response to Pseudomonas aeruginosa infection.PMID 23212155Read ↗

A conserved p38 MAP kinase pathway in Caenorhabditis elegans innate immunity.Semantic proximity Read ↗

The p38 MAPK/PMK-1 Pathway Is Required for Resistance to Nocardia farcinica Infection in Caenorhabditis eleganceSemantic proximity Read ↗

Isolation and characterization of pmk-(1-3): three p38 homologs in Caenorhabditis elegans.Semantic proximity Read ↗

p38 MAPK regulates expression of immune response genes and contributes to longevity in C. elegans.Semantic proximity Read ↗

RACK-1, a multifaceted regulator is required for C. elegans innate immunity against S. flexneri M9OT infection.Semantic proximity Read ↗

Aberrant Activation of p38 MAP Kinase-Dependent Innate Immune Responses Is Toxic to Caenorhabditis elegans.Semantic proximity Read ↗

Genetic analysis of JNK MAPK signaling in stress-induced avoidance behavior in C. elegans.Semantic proximity Read ↗

An essential role for XBP-1 in host protection against immune activation in C. elegans.Semantic proximity Read ↗

Neural regulation of immunity: role of NPR-1 in pathogen avoidance and regulation of innate immunity.Semantic proximity Read ↗

In the Model Host Caenorhabditis elegans, Sphingosine-1-Phosphate-Mediated Signaling Increases Immunity toward Human Opportunistic Bacteria.Semantic proximity Read ↗

Caenorhabditis elegans innate immune response triggered by Salmonella enterica requires intact LPS and is mediated by a MAPK signaling pathway.Semantic proximity Read ↗

Deficiency of Innate Immunity against Pseudomonas aeruginosa Enhances Behavioral Avoidance via the HECW-1/NPR-1 Module in Caenorhabditis elegans.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.