Article
The 9p21.3 locus and cardiovascular risk in familial hypercholesterolemia.
Journal of clinical lipidology - 1 Jan 2000
Paquette Martine, Chong Michael, Saavedra Yascara Grisel Luna, Paré Guillaume, Dufour Robert, Baass Alexis
Abstract excerpt
BACKGROUND: Carrying a risk variant in the 9p21.3 locus represents one of the strongest genetic risk factors for atherosclerotic cardiovascular disease (ASCVD) in the general population. However, the effect of these polymorphisms in patients with familial hypercholesterolemia (FH) has never been studied. OBJECTIVE: The objective of this study was to investigate the association between the sentinel 9p21.3 single...
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