Association between the coronary artery disease risk locus on chromosome 9p21.3 and abdominal aortic aneurysm.

doi:10.1161/CIRCGENETICS.108.789727

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Article

Association between the coronary artery disease risk locus on chromosome 9p21.3 and abdominal aortic aneurysm.

Circulation. Cardiovascular genetics - 1 Oct 2008

Bown Matthew J, Braund Peter S, Thompson John, London Nicholas J M, Samani Nilesh J, Sayers Robert D

Abstract excerpt

BACKGROUND: Recent genome-wide studies have shown a significant association of a locus on chromosome 9p21.3 and coronary artery disease. We performed a case-control study to investigate the association between this locus and abdominal aortic aneurysm (AAA). METHODS AND RESULTS: A total of 1714 patients (899 patients with AAA and 815 controls) were genotyped for the lead single-nucleotide polymorphism, rs1333049,...

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PMID: 20031540
DOI: 10.1161/CIRCGENETICS.108.789727

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