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Article

The Association between Serum LDL Cholesterol and Genetic Variation in Chromosomal Locus 1p13.3 among Coronary Artery Disease Patients.

BioMed research international - 1 Jan 2015

Rizk Nasser M, El-Menyar Ayman, Egue Huda, Souleman Wais Idil, Mohamed Baluli Hissa, Alali Khalid, Farag Fathi, Younes Noura, Al Suwaidi Jassim

Abstract excerpt

BACKGROUND: Several polymorphisms of a locus on chromosome 1p13.3 have a significant effect on low-density lipoprotein cholesterol (LDL-C), atherosclerosis, and acute coronary syndrome (ACS). METHODS: We aimed to investigate the association between rs599839, rs646776, and rs4970834 of locus 1p13.3 and serum LDL-C and severity of coronary artery stenosis in ACS patients. Genotyping of the rs599839, rs646776, and...

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Topics

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Aged
Alleles
Cholesterol, LDL
Chromosomes, Human, Pair 1
Coronary Artery Disease
Genetic Loci
Polymorphism, Genetic

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Open in PubMed Open full text

Identifiers

PMID: 25969834
DOI: 10.1155/2015/678924
PMCID: PMC4370099

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