Article
Analysis on the polymorphisms of site RS4977574, and RS1333045 in region 9p21 and the susceptibility of coronary heart disease in Chinese population.
BMC medical genetics - 17 Feb 2020
Hua Lei, Yuan Jin-Xia, He Shu, Zhao Chen-Hui, Jia Qiao-Wei, Zhang Jing, An Feng-Hui, Chen Zhao-Hong, Li Li-Hua, Wang Lian-Sheng, Ma Wen-Zhu, Xu Guang-Xu, Jia En-Zhi
Abstract excerpt
BACKGROUND: Rs4977574 (A > G) and Rs1333045 (C > T) are both single nucleotide polymorphisms (SNPs) related with coronary artery disease, locating on chromosome 9p21.3. The study aimed to identify the correlation between rs4977574 and rs1333045 polymorphism genotypes and coronary heart disease (CHD) in a Chinese population. METHODS: Blood samples were collected from 855 subjects. A case-control study was used in...