Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Humanized NOG mice as a model for tuberculosis vaccine-induced immunity: a comparative analysis with the mouse and guinea pig models of tuberculosis.

Immunology - 1 Sept 2017

Grover Ajay, Troy Amber, Rowe Jenny, Troudt JoLynn M, Creissen Elizabeth, McLean Jennifer, Banerjee Prabal, Feuer Gerold, Izzo Angelo A

Abstract excerpt

The humanized mouse model has been developed as a model to identify and characterize human immune responses to human pathogens and has been used to better identify vaccine candidates. In the current studies, the humanized mouse was used to determine the ability of a vaccine to affect the immune response to infection with Mycobacterium tuberculosis. Both human CD4+ and CD8+ T cells responded to infection in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to BCG Vaccine
Share to Guinea Pigs

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Leukocyte Common Antigens

Share to Mesenchymal Stem Cell Transplantation

Share to Mice, Inbred NOD

Share to Oligodeoxyribonucleotides

Share to Tuberculosis, Pulmonary

Share to Vaccination

Source

Open in PubMed Open full text

Identifiers

PMID: 28502122
DOI: 10.1111/imm.12756
PMCID: PMC5543476

Genes

NOG

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Humanized NOG mice as a model for tuberculosis vaccine-induced immunity: a comparative analysis with the mouse and guinea pig models of tuberculosis.PMID 28502122Read ↗

Humanized mice for the study of infectious diseasesSemantic proximity Read ↗

Humanized mouse models of immunological diseases and precision medicineSemantic proximity Read ↗

Humanized mice in infectious diseasesSemantic proximity Read ↗

Modeling Infectious Diseases in Mice with a “Humanized” Immune SystemSemantic proximity Read ↗

Mouse models with human immunity and their application in biomedical researchSemantic proximity Read ↗

Mice with human immune system components as <i>in vivo</i> models for infections with human pathogensSemantic proximity Read ↗

Protection against Tuberculosis with Homologous or Heterologous Protein/Vector Vaccine Approaches Is Not Dependent on CD8+ T CellsSemantic proximity Read ↗

BCG Vaccination Induces Trained Innate Immunity in Adults Over 50 Years of Age: A Randomized Trial in Guinea-BissauSemantic proximity Read ↗

A humanized mouse model identifies key amino acids for low immunogenicity of H7N9 vaccines.Semantic proximity Read ↗

Attenuated P. falciparum Parasite Shows Cytokine Variations in Humanized Mice.Semantic proximity Read ↗

Mycolic acid-specific T cells protect against Mycobacterium tuberculosis infection in a humanized transgenic mouse modelSemantic proximity Read ↗

A mouse model for the human pathogen Salmonella typhi.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.