Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Attenuated P. falciparum Parasite Shows Cytokine Variations in Humanized Mice.

Frontiers in immunology - 1 Jan 2020

Zhang Lei-Lei, Li Jin-Long, Ji Ming-Xin, Tian Dan, Wang Li-Yan, Chen Chen, Tian Miao

Abstract excerpt

A recently developed humanized mouse has been used to assess the immune response evoked against the isolated attenuated C9 parasite clone (C9-M; carrying a single insertion disrupting the open reading frame (ORF) of PF3D7_1305500) of Plasmodium falciparum. Significant human RBC engraftment was achieved by ameliorating the residual non-adaptive immune response using clodronate-loaded liposome treatment. Controlled...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Erythrocyte Transfusion
Share to Erythrocytes
Share to Host-Parasite Interactions

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Immune Evasion

Share to Malaria, Falciparum

Share to Mice, Inbred NOD

Share to Mice, SCID

Share to Parasite Load

Source

Open in PubMed Open full text

Identifiers

PMID: 33013831
DOI: 10.3389/fimmu.2020.01801
PMCID: PMC7516016

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Attenuated P. falciparum Parasite Shows Cytokine Variations in Humanized Mice.PMID 33013831Read ↗

A Hitchhiker's guide to humanized mice: new pathways to studying viral infections.Semantic proximity Read ↗

Modeling malaria in humanized mice: opportunities and challengesSemantic proximity Read ↗

Selective expression of variant surface antigens enables Plasmodium falciparum to evade immune clearance in vivoSemantic proximity Read ↗

Selective Expression of Variant Surface Antigens Enables <i>Plasmodium falciparum</i> to Evade Immune Clearance <i>in vivo</i>Semantic proximity Read ↗

Humanized mice for the study of infectious diseasesSemantic proximity Read ↗

Human Malaria in Immunocompromised MiceSemantic proximity Read ↗

Humanized HLA-DR4.RagKO.IL2RγcKO.NOD (DRAG) mice sustain the complex vertebrate life cycle of Plasmodium falciparum malariaSemantic proximity Read ↗

Plasmodium falciparum infection and exoerythrocytic development in mice with chimeric human liversSemantic proximity Read ↗

Complete Plasmodium falciparum liver-stage development in liver-chimeric miceSemantic proximity Read ↗

Distinct placental malaria pathology caused by different Plasmodium berghei lines that fail to induce cerebral malaria in the C57BL/6 mouseSemantic proximity Read ↗

Analysis of innate defences against Plasmodium falciparum in immunodeficient mice.Semantic proximity Read ↗

Improved Murine Model of Malaria Using<i>Plasmodium falciparum</i>Competent Strains and Non-Myelodepleted NOD-<i>scid IL2R</i>γ<sup><i>null</i></sup>Mice Engrafted with Human ErythrocytesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.