Article
Genetic variation in tissue inhibitors of metalloproteinases as a risk factor for idiopathic recurrent spontaneous abortion.
Fertility and sterility - 1 Jun 2013
Pereza Nina, Volk Marija, Zrakić Nikolina, Kapović Miljenko, Peterlin Borut, Ostojić Saša
Abstract excerpt
OBJECTIVE: To investigate the potential association of tissue inhibitor of metalloproteinases (TIMP) 1, 2, 3, and 4 gene polymorphisms with idiopathic recurrent spontaneous abortion (IRSA). DESIGN: Case-control and association study. SETTING: Departments of gynecology and obstetrics and university-based research laboratory. PATIENT(S): A total of 149 couples with a history of three or more idiopathic spontaneous...
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