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Article

Association study of five functional polymorphisms in matrix metalloproteinase-2, -3, and -9 genes with risk of primary ovarian insufficiency in Korean women.

Maturitas - 1 Feb 2015

Kim Young Ran, Jeon Young Joo, Kim Hyun Seok, Kim Jung O, Moon Myoung Jin, Ahn Eun Hee, Lee Woo Sik, Kim Nam Keun

Abstract excerpt

OBJECTIVE: Primary ovarian insufficiency (POI) is diagnosed clinically by increased follicle-stimulating hormone (FSH) levels and estradiol (E2) deficiency. A previous report suggests a possible association matrix metalloproteinase (MMP) and estrogen signaling pathway; however, there are no reports of MMP genetic associations with POI. STUDY DESIGN: Blood samples were collected from 374 karyotypically normal...

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PMID: 25482733
DOI: 10.1016/j.maturitas.2014.11.008

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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