Article
Association of MMP-2, MMP-3, and MMP-9 Polymorphisms with Susceptibility to Recurrent Pregnancy Loss.
Fetal and pediatric pathology - 1 Oct 2021
Behforouz Athena, Dastgheib Seyed Alireza, Abbasi Hajar, Karimi-Zarchi Mojgan, Javaheri Atiyeh, Hadadan Amaneh, Tabatabaei Razieh Sadat, Meibodi Bahare, Neamatzadeh Hossein
Abstract excerpt
BACKGROUND: Genetic causes that contribute to recurrent pregnancy loss (RPL) are not fully understood. The aim of this study was to evaluate the association of five polymorphisms at MMP-2, MMP-3, and MMP-9 genes with risk of RPL. Methods: The study comprised 250 women with RPL and 250 healthy controls. The MMP-2 (rs243865, rs2285053), MMP-3 (rs35068180), and MMP 9 (rs3918242, rs17576) polymorphisms were genotyped...