Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

SAR1a promoter polymorphisms are not associated with fetal hemoglobin in patients with sickle cell disease from Cameroon.

BMC research notes - 12 May 2017

Pule Gift Dineo, Bitoungui Valentina Josiane Ngo, Chemegni Bernard Chetcha, Kengne Andre Pascal, Wonkam Ambroise

Abstract excerpt

BACKGROUND: Reactivation of adult hemoglobin (HbF) is currently a dominant therapeutic approach to sickle cell disease (SCD). In this study, we have investigated among SCD patients from Cameroon, the association of HbF level and variants in the HU-inducible small guanosine triphosphate-binding protein, secretion-associated and RAS-related (SAR1a) protein, previously shown to be associated with HbF after HU...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Anemia, Sickle Cell
Share to Cameroon

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Child, Preschool

Share to Fetal Hemoglobin

Share to Haplotypes

Share to Monomeric GTP-Binding Proteins

Share to Promoter Regions, Genetic

Share to Young Adult

Source

Open in PubMed Open full text

Identifiers

PMID: 28499394
DOI: 10.1186/s13104-017-2502-3
PMCID: PMC5427596

Genes

SCD
HBB

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

SAR1a promoter polymorphisms are not associated with fetal hemoglobin in patients with sickle cell disease from Cameroon.PMID 28499394Read ↗

Fetal haemoglobin response to hydroxycarbamide treatment and sar1a promoter polymorphisms in sickle cell anaemia.Semantic proximity Read ↗

Association of variants at BCL11A and HBS1L-MYB with hemoglobin F and hospitalization rates among sickle cell patients in Cameroon.Semantic proximity Read ↗

Association between Variants at BCL11A Erythroid-Specific Enhancer and Fetal Hemoglobin Levels among Sickle Cell Disease Patients in Cameroon: Implications for Future Therapeutic Interventions.Semantic proximity Read ↗

ANTXR1 Intronic Variants Are Associated with Fetal Hemoglobin in the Arab-Indian Haplotype of Sickle Cell Disease.Semantic proximity Read ↗

Fetal haemoglobin in sickle-cell disease: from genetic epidemiology to new therapeutic strategies.Semantic proximity Read ↗

Fetal hemoglobin in sickle cell anemia: genetic studies of the Arab-Indian haplotype.Semantic proximity Read ↗

Fetal hemoglobin in sickle cell anemia: The Arab-Indian haplotype and new therapeutic agents.Semantic proximity Read ↗

A candidate transacting modulator of fetal hemoglobin gene expression in the Arab-Indian haplotype of sickle cell anemia.Semantic proximity Read ↗

Perspectives in Genetics and Sickle Cell Disease Prevention in Africa: Beyond the Preliminary Data from Cameroon.Semantic proximity Read ↗

Gene polymorphisms predicting response to hydroxyurea treatment in Bahraini patients with sickle cell disease.Semantic proximity Read ↗

Promoter region sequence differences in the A and G gamma globin genes of Brazilian sickle cell anemia patients.Semantic proximity Read ↗

Genotyping the BCL11A Single Nucleotide Polymorphism and Associated Levels of Fetal Hemoglobin in Mauritanian Sickle Cell Patients.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.