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Article

CD44 variant isoform 9 emerges in response to injury and contributes to the regeneration of the gastric epithelium.

The Journal of pathology - 1 Aug 2017

Bertaux-Skeirik Nina, Wunderlich Mark, Teal Emma, Chakrabarti Jayati, Biesiada Jacek, Mahe Maxime, Sundaram Nambirajan, Gabre Joel, Hawkins Jennifer, Jian Gao, Engevik Amy C, Yang Li, Wang Jiang, Goldenring James R, Qualls Joseph E, Medvedovic Mario, Helmrath Michael A, Diwan Tayyab, Mulloy James C, Zavros Yana

Abstract excerpt

The CD44 gene encodes several protein isoforms due to alternative splicing and post translational modifications. Given that CD44 variant isoform 9 (CD44v9) is expressed within Spasmolytic Polypeptide/TFF2-Expressing Metaplasia (SPEM) glands during repair, CD44v9 may be play a funcitonal role during the process of regeneration of the gastric epithelium. Here we hypothesize that CD44v9 marks a regenerative cell...

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Share to Hyaluronan Receptors
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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 28497484
DOI: 10.1002/path.4918
PMCID: PMC5591948

Genes

TFF2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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