Article

Heterogeneity in mouse SPEM lineages identifies markers of metaplastic progression

2012-07-07

Abstract excerpt

OBJECTIVES:\nSpasmolytic polypeptide-expressing metaplasia (SPEM) develops as a preneoplastic lesion in the stomachs of mice and humans after parietal cell loss. To identify the commonalities and differences between phenotypic SPEM lineages, SPEM were studied from three different mouse models of parietal cell loss: with chronic inflammation with Helicobacter felis infection; with acute inflammation with L635 treat...

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Literature Corpus work: 396c1b85-876c-5373-8287-7ca416b9e74d
DOI: 10.1136/gutjnl-2012-302401

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