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Article

WFDC2 Promotes Spasmolytic Polypeptide-Expressing Metaplasia Through the Up-Regulation of IL33 in Response to Injury.

Gastroenterology - 1 Sept 2021

Jeong Haengdueng, Lee Buhyun, Kim Kwang H, Cho Soo Young, Cho Yejin, Park Jeongeun, Lee Yura, Oh Yeseul, Hwang Bo Ram, Jang Ah-Ra, Park Jong-Hwan, Park Ji-Ho, Jeong Sang-Ho, Lee Daekee, Lee Yong Chan, Lim Kyung-Min, Goldenring James R, Nam Ki Taek

Abstract excerpt

BACKGROUND & AIMS: WAP 4-disulfide core domain protein 2 (WFDC2), also known as human epididymis protein 4, is a small secretory protein that is highly expressed in fibrosis and human cancers, particularly in the ovaries, lungs, and stomach. However, the role of WFDC2 in carcinogenesis is not fully understood. The present study aimed to investigate the role of WFDC2 in gastric carcinogenesis with the use of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 34116028
DOI: 10.1053/j.gastro.2021.05.058
PMCID: PMC8380710

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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