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Article

Candidate susceptibility variants for esophageal squamous cell carcinoma.

Genes, chromosomes & cancer - 1 Jun 2017

Donner Iikki, Katainen Riku, Tanskanen Tomas, Kaasinen Eevi, Aavikko Mervi, Ovaska Kristian, Artama Miia, Pukkala Eero, Aaltonen Lauri A

Abstract excerpt

Esophageal cancer is common worldwide, and often fatal. The major histological subtype is esophageal squamous cell carcinoma (ESCC). ESCC shows familial aggregation and high heritability. Mutations in RHBDF2 cause tylosis, a very rare disorder characterized by high life-time risk of ESCC, but no other well-established predisposition genes have been identified. To identify candidate susceptibility variants for...

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Source

Identifiers

PMID: 28165652
DOI: 10.1002/gcc.22448

Genes

DNAH9
BAG1
DDOST
GKAP1
NFX1
RHBDF2

Variants

Provenance

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