Article
Replication of a genome-wide case-control study of esophageal squamous cell carcinoma.
International journal of cancer - 1 Oct 2008
Ng David, Hu Nan, Hu Ying, Wang Chaoyu, Giffen Carol, Tang Ze-Zhong, Han Xiao-You, Yang Howard H, Lee Maxwell P, Goldstein Alisa M, Taylor Philip R
Abstract excerpt
In a previous pilot case-control study of individuals diagnosed with esophageal squamous cell carcinoma (ESCC) and matched controls from a high-risk area in China, we identified 38 single nucleotide polymorphisms (SNPs) associated with ESCC located in or near one of 33 genes. In our study, we attempted to replicate the results of these 38 gene-related SNPs in a new sample of 300 ESCC cases and 300 matched...
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