Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Combining new tools to assess renal function and morphology: a holistic approach to study the effects of aging and a congenital nephron deficit.

American journal of physiology. Renal physiology - 1 Sept 2017

Geraci Stefania, Chacon-Caldera Jorge, Cullen-McEwen Luise, Schad Lothar R, Sticht Carsten, Puelles Victor G, Bertram John F, Gretz Norbert

Abstract excerpt

Recently, new methods for assessing renal function in conscious mice (transcutaneous assessment) and for counting and sizing all glomeruli in whole kidneys (MRI) have been described. In the present study, these methods were used to assess renal structure and function in aging mice, and in mice born with a congenital low-nephron endowment. Age-related nephron loss was analyzed in adult C57BL/6 mice (10-50 wk of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Fluoresceins
Share to Glial Cell Line-Derived Neurotrophic Factor

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Half-Life

Share to Hypertrophy

Share to Kidney Function Tests

Share to Kidney Glomerulus

Share to Nephrons

Share to Oligosaccharides

Source

Identifiers

PMID: 28490528
DOI: 10.1152/ajprenal.00329.2015

Genes

GDNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Combining new tools to assess renal function and morphology: a holistic approach to study the effects of aging and a congenital nephron deficit.PMID 28490528Read ↗

Nephron number, renal function, and arterial pressure in aged GDNF heterozygous mice.Semantic proximity Read ↗

Nanoscale Optical Imaging, Reconstruction, and Spatial Analysis of Whole Mouse GlomeruliSemantic proximity Read ↗

Glomerular number and size variability and risk for kidney diseaseSemantic proximity Read ↗

Aging and senescence-associated analysis of the aged kidney glomerulus highlights the role of mesangial cells in renal agingSemantic proximity Read ↗

Quantifiable and reproducible phenotypic assessment of a constitutive knockout mouse model for congenital nephrotic syndrome of the Finnish type.Semantic proximity Read ↗

Analysis of Nephron Composition and Function in the Adult Zebrafish KidneySemantic proximity Read ↗

Nephron number, hypertension, and CKD: physiological and genetic insight from humans and animal modelsSemantic proximity Read ↗

High nephron endowment protects against salt-induced hypertension.Semantic proximity Read ↗

Three dimensional multiscalar neurovascular nephron connectivity map of the human kidney across the lifespanSemantic proximity Read ↗

Nephron endowment in glial cell line-derived neurotrophic factor (GDNF) heterozygous mice.Semantic proximity Read ↗

Six months of physical inactivity is insufficient to cause chronic kidney disease in C57BL/6J miceSemantic proximity Read ↗

Non-Transgenic Mouse Models of Kidney Disease.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.