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Donor and recipient chemokine receptor CCR5 genotype is associated with survival after bone marrow transplantation

13 Jan 2010

Abstract excerpt

Despite continual improvement, morbidity and mortality after hematopoietic stem cell transplantation (HSCT) remain high. The importance of chemokines in HSCT lies in their regulation of immune responses that determine transplantation outcomes. We investigated the role of recipient and donor chemokine system gene polymorphisms by using a candidate gene approach on the incidence of graft-versus-host disease and...

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Share to Chemokine receptors and signaling
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PMID: 20068218
DOI: 10.1182/blood-2009-08-237768

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