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Article

Inflammatory state exists in familial amyloid polyneuropathy that may be triggered by mutated transthyretin.

Scientific reports - 8 May 2017

Suenaga Genki, Ikeda Tokunori, Masuda Teruaki, Motokawa Hiroaki, Yamashita Taro, Takamatsu Kotaro, Misumi Yohei, Ueda Mitsuharu, Matsui Hirotaka, Senju Satoru, Ando Yukio

Abstract excerpt

The relationship between familial amyloid polyneuropathy (FAP), which is caused by mutated transthyretin (TTR), and inflammation has only recently been noted. To determine whether inflammation is present in FAP carriers and patients, serum interleukin (IL)-6 concentration in 57 healthy donors (HD), 21 FAP carriers, and 66 FAP patients was examined, with the relationship between IL-6 and TTR assessed in each group...

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Share to Amyloid Neuropathies, Familial
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 28484271
DOI: 10.1038/s41598-017-01775-4
PMCID: PMC5431548

Genes

FAP
TTR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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