Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Exploring the role of glial fibrillary acid protein and neurofilament light chains in patients with hereditary transthyretin amyloidosis with polyneuropathy.

Diagnosis (Berlin, Germany) - 1 Feb 2026

Gambino Caterina Maria, Agnello Luisa, Di Stefano Vincenzo, Del Ben Fabio, Masucci Anna, Tamburello Martina, Vassallo Roberta, Scazzone Concetta, Ciaccio Anna Maria, Brighina Filippo, Ciaccio Marcello

Abstract excerpt

OBJECTIVES: Hereditary transthyretin amyloidosis with polyneuropathy (ATTRv-PN) is a rare, progressive neurodegenerative disorder caused by mutations in the transthyretin (TTR) gene. The disease leads to systemic amyloid deposition, primarily affecting the nervous system and, in some cases, the heart. Early diagnosis and monitoring are critical for effective management, yet reliable biomarkers remain limited....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged
Share to Amyloid Neuropathies, Familial

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Biomarkers

Share to Case-Control Studies

Share to Glial Fibrillary Acidic Protein

Share to Neurofilament Proteins

Share to Polyneuropathies

Share to Prealbumin

Source

Identifiers

PMID: 40488235
DOI: 10.1515/dx-2025-0042

Genes

GFAP
TTR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Exploring the role of glial fibrillary acid protein and neurofilament light chains in patients with hereditary transthyretin amyloidosis with polyneuropathy.PMID 40488235Read ↗

Neurofilament Light Chain in Systemic Amyloidosis: A Systematic ReviewSemantic proximity Read ↗

Serum neurofilament light chain: a promising early diagnostic biomarker for hereditary transthyretin amyloidosis?Semantic proximity Read ↗

Plasma neurofilament light chain: an early biomarker for hereditary ATTR amyloid polyneuropathy.Semantic proximity Read ↗

Serum Neurofilament Light Chain Is Not an Independent Predictor of Autonomic Neuropathy in Hereditary Transthyretin AmyloidosisSemantic proximity Read ↗

Cutaneous nerve biomarkers in transthyretin familial amyloid polyneuropathy.Semantic proximity Read ↗

Transthyretin familial amyloid polyneuropathy: an update.Semantic proximity Read ↗

Clinical features of TTR-FAP in PortugalSemantic proximity Read ↗

The neuropathy in hereditary transthyretin amyloidosis: A narrative review.Semantic proximity Read ↗

Comprehensive cross-sectional and longitudinal comparisons of plasma glial fibrillary acidic protein and neurofilament light across FTD spectrum disordersSemantic proximity Read ↗

The role of blood-based biomarkers in Parkinsonian disorders, Alzheimer's disease and frontotemporal dementiaSemantic proximity Read ↗

Single-centre experience on transthyretin familial amyloid polyneuropathy: case series and literature review.Semantic proximity Read ↗

Glial cells in familial amyloidotic polyneuropathy.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.