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Pancreatic Islet Protein Complexes and Their Dysregulation in Type 2 Diabetes

20 Apr 2017

Abstract excerpt

Type 2 diabetes (T2D) is a complex disease that involves multiple genes. Numerous risk loci have already been associated with T2D, although many susceptibility genes remain to be identified given heritability estimates. Systems biology approaches hold potential for discovering novel T2D genes by considering their biological context, such as tissue-specific protein interaction partners. Pancreatic islets are a key...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 28473845
DOI: 10.3389/fgene.2017.00043

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