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Article

Diabetic embryopathy: A role for the epigenome?

2 May 2011

Abstract excerpt

Embryonic development under adverse conditions, such as maternal diabetes or obesity during pregnancy, constitutes a major risk factor for birth defects, as well as for long-term health consequences and disease susceptibility in the offspring. While contributions from epigenetic changes have been invoked previously to explain the long-term changes in terms of developmental programming, we here review how maternal...

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PMID: 21538816
DOI: 10.1002/bdra.20807

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