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Maternal obesity and gestational diabetes reprogram the methylome of offspring beyond birth by inducing epigenetic signatures in metabolic and developmental pathways

4 Mar 2023

Abstract excerpt

BACKGROUND: Obesity is a negative chronic metabolic health condition that represents an additional risk for the development of multiple pathologies. Epidemiological studies have shown how maternal obesity or gestational diabetes mellitus during pregnancy constitute serious risk factors in relation to the appearance of cardiometabolic diseases in the offspring. Furthermore, epigenetic remodelling may help explain...

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Share to Birth, Development, and Health
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 36870961
DOI: 10.1186/s12933-023-01774-y

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