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Article

CYP2C19 loss-of-function variants are independent risk factors for premature cerebral infarction: a hospital based retrospective study.

BMC cardiovascular disorders - 29 Oct 2024

Shi Yuliang, Yang Yuxian, Feng Miaoling, Wu Heming

Abstract excerpt

OBJECTIVE: Cytochrome P450 2C19 (CYP2C19) plays an vital role in the course of cardiovascular and cerebrovascular diseases by affecting lipid metabolism. Triglyceride-glucose (TyG) is a comprehensive index composed of triglyceride and blood glucose, has relationship with some diseases. There was no research report on the association CYP2C19 polymorphisms, TyG with premature cerebral infarction (CI) (onset ≤ 65...

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Identifiers

PMID: 39472784
DOI: 10.1186/s12872-024-04269-0
PMCID: PMC11520391

Genes

CYP2C19
TG

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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