Article
Gender differences in impact of CYP2C19 polymorphism on development of coronary artery disease.
Journal of cardiovascular pharmacology - 1 Feb 2015
Hokimoto Seiji, Tabata Noriaki, Akasaka Tomonori, Arima Yuichiro, Kaikita Koichi, Morita Kazunori, Kumagae Naoki, Oniki Kentaro, Nakagawa Kazuko, Ogawa Hisao
Abstract excerpt
The aim was to clarify whether CYP2C19 polymorphism is associated with the development of coronary artery disease (CAD). This study enrolled 723 patients with CAD (men 71%, 70 years) and healthy subjects undergoing a medical checkup (n = 453) as controls (men 69%, 53 years). We analyzed the incidence of CYP2C19 polymorphism and its association with the development of CAD in the absence of diabetes, dyslipidemia,...
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