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Article

The CpG island methylator phenotype is concordant between primary colorectal carcinoma and matched distant metastases.

Clinical epigenetics - 1 Jan 2017

Cohen Stacey A, Yu Ming, Baker Kelsey, Redman Mary, Wu Chen, Heinzerling Tai J, Wirtz Ralph M, Charalambous Elpida, Pentheroudakis George, Kotoula Vassiliki, Kalogeras Konstantine T, Fountzilas George, Grady William M

Abstract excerpt

BACKGROUND: The CpG island methylator phenotype (CIMP) in stage III colon cancer (CRC) has been associated with improved survival after treatment with adjuvant irinotecan-based chemotherapy. In this analysis, we determine whether CIMP status in the primary CRC is concordant with the CIMP status of matched metastases in order to determine if assessment of CIMP status in the primary tumor can be used to predict...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 28469732
DOI: 10.1186/s13148-017-0347-1
PMCID: PMC5414304

Genes

IGF2
NEUROG1
RUNX3
SOCS1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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