Article
Cutting edge genomics reveal new insights into tumour development, disease progression and therapeutic impacts in multiple myeloma.
British journal of haematology - 1 Jul 2017
Dutta Ankit K, Hewett Duncan R, Fink J Lynn, Grady John P, Zannettino Andrew C W
Abstract excerpt
Multiple Myeloma (MM) is a haematological malignancy characterised by the clonal expansion of plasma cells (PCs) within the bone marrow. Despite advances in therapy, MM remains a largely incurable disease with a median survival of 6 years. In almost all cases, the development of MM is preceded by the benign PC condition Monoclonal Gammopathy of Undetermined Significance (MGUS). Recent studies show that the...
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