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Interaction of CEND1 gene and life events in susceptibility to depressive symptoms in Chinese Han college students.

Journal of affective disorders - 1 Jan 2021

Hou Binyin, Ji Lei, Chen Zhixuan, An Lin, Zhang Naixin, Ren Decheng, Yuan Fan, Liu Liangjie, Bi Yan, Guo Zhenming, Ma Gaini, Xu Fei, Yang Fengping, Yu Shunying, Yi Zhenghui, Xu Yifeng, He Lin, Liu Chuanxin, Bai Bo, Yu Tao, Wu Shaochang, Zhao Longyou, Cai Changqun, Wu Xi, Li Xingwang, He Guang

Abstract excerpt

BACKGROUND: . The development of depressive symptoms (DSs) is a complex process caused by both genetic and environmental factors. CEND1 gene coordinates cell division, differentiation and maturation of neural precursor cells, which affects brain structure and function. Our study investigated whether CEND1 was a genetic factor for DSs, particularly under negative life events. METHODS: . 272 freshmen with DSs and...

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PMID: 33027701
DOI: 10.1016/j.jad.2020.09.082

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