Article
Isolation and identification of senescent renal tubular epithelial cells using immunomagnetic beads based on DcR2.
Experimental gerontology - 1 Sept 2017
Chen Jia, Chen Ke-Hong, Fu Bi-Qiong, Zhang Weiwei, Dai Huanzi, Lin Li-Rong, Wang Li-Ming, He Ya-Ni
Abstract excerpt
Cell senescence plays a major role in the progression of tumors and chronic conditions such as diabetes and chronic kidney disease. Senescent cells are an important model for the study of aging-related diseases, and there is currently no efficient method for sorting out senescent cells. Decoy receptor 2 (DcR2) is a transmembrane receptor of the tumor necrosis factor superfamily, which is specifically expressed in...
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