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Article

Enhanced nasopharyngeal infection and shedding associated with an epidemic lineage of emm3 group A Streptococcus.

Virulence - 3 Oct 2017

Afshar Baharak, Turner Claire E, Lamagni Theresa L, Smith Ken C, Al-Shahib Ali, Underwood Anthony, Holden Matthew T G, Efstratiou Androulla, Sriskandan Shiranee

Abstract excerpt

BACKGROUND: A group A Streptococcus (GAS) lineage of genotype emm3, sequence type 15 (ST15) was associated with a 6 month upsurge in invasive GAS disease in the UK. The epidemic lineage (Lineage C) had lost 2 typical emm3 prophages, Φ315.1 and Φ315.2 associated with the superantigen ssa, but gained a different prophage (ΦUK-M3.1) associated with a different superantigen, speC and a DNAse spd1. METHODS AND...

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Identifiers

PMID: 28459299
DOI: 10.1080/21505594.2017.1325070
PMCID: PMC5711448

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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