Article
Genome-wide molecular dissection of serotype M3 group A Streptococcus strains causing two epidemics of invasive infections.
Proceedings of the National Academy of Sciences of the United States of America - 10 Aug 2004
Beres Stephen B, Sylva Gail L, Sturdevant Daniel E, Granville Chanel N, Liu Mengyao, Ricklefs Stacy M, Whitney Adeline R, Parkins Larye D, Hoe Nancy P, Adams Gerald J, Low Donald E, DeLeo Frank R, McGeer Allison, Musser James M
Abstract excerpt
Molecular factors that contribute to the emergence of new virulent bacterial subclones and epidemics are poorly understood. We hypothesized that analysis of a population-based strain sample of serotype M3 group A Streptococcus (GAS) recovered from patients with invasive infection by using genome-wide investigative methods would provide new insight into this fundamental infectious disease problem. Serotype M3 GAS...
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