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Article

Novel candidate genes may be possible predisposing factors revealed by whole exome sequencing in familial esophageal squamous cell carcinoma.

Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 May 2017

Forouzanfar Narjes, Baranova Ancha, Milanizadeh Saman, Heravi-Moussavi Alireza, Jebelli Amir, Abbaszadegan Mohammad Reza

Abstract excerpt

Esophageal squamous cell carcinoma is one of the deadliest of all the cancers. Its metastatic properties portend poor prognosis and high rate of recurrence. A more advanced method to identify new molecular biomarkers predicting disease prognosis can be whole exome sequencing. Here, we report the most effective genetic variants of the Notch signaling pathway in esophageal squamous cell carcinoma susceptibility by...

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Share to Carcinoma, Squamous Cell
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 28459198
DOI: 10.1177/1010428317699115

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MET

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