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Article

Gene mutations of esophageal squamous cell carcinoma based on next-generation sequencing.

Chinese medical journal - 25 Feb 2021

Wang Long, Jia Yi-Meng, Zuo Jing, Wang Yu-Dong, Fan Zhi-Song, Feng Li, Zhang Xue, Han Jing, Lyu Wen-Jing, Ni Zhi-Yu

Abstract excerpt

BACKGROUND: Esophageal squamous cell carcinoma (ESCC) is one of the most aggressive cancers without effective therapy. To explore potential molecular targets in ESCC, we quantified the mutation spectrum and explored the relationship between gene mutation and clinicopathological characteristics and programmed death-ligand 1 (PD-L1) expression. METHODS: Between 2015 and 2019, 29 surgically resected ESCC tissues and...

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Share to B7-H1 Antigen
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 33725708
DOI: 10.1097/CM9.0000000000001411
PMCID: PMC7990006

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