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Article

Genomic analyses reveal SCN7A is associated with the prognosis of esophageal squamous cell carcinoma.

Esophagus : official journal of the Japan Esophageal Society - 1 Apr 2022

Yuan Ping, Rao Wenqing, Lin Zheng, Liu Shuang, Lin Xiuquan, Wu Chaofeng, Lin Xu, Hu Zhijian, Ye Weimin

Abstract excerpt

BACKGROUND: Esophageal squamous cell carcinoma (ESCC) has a poor prognosis and occurs with high frequency in China. In particular, Fujian is one of the high-incidence areas of ESCC in China and the somatic mutation profile of ESCC there remains unclear. PATIENTS AND METHODS: Whole-exome sequencing (WES) was performed in 49 matched ESCC tumor-normal specimens to examine the somatic mutation profiles. Hazard ratios...

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PMID: 34993672
DOI: 10.1007/s10388-021-00898-y

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