Article
Interleukin 1 receptor antagonist polymorphisms are associated with the risk of developing acute coronary syndrome in Mexicans.
Immunology letters - 30 Oct 2010
Fragoso José Manuel, Delgadillo Hilda, Llorente Luis, Chuquiure Eduardo, Juárez-Cedillo Teresa, Vallejo Maite, Lima Guadalupe, Furuzawa-Carballeda Janette, Peña-Duque Marco Antonio, Martínez-Ríos Marco Antonio, Vargas-Alarcón Gilberto
Abstract excerpt
Inflammation plays an essential role in the development and progression of atherosclerotic lesions. Cytokines of the interleukin-1 family are central regulators in immunoinflammatory mechanisms. In the present work, the role of interleukin 1 (IL-1) and IL-1 receptor antagonist (IL-1RN) gene polymorphisms as susceptibility markers for acute coronary syndrome (ACS) was evaluated. Six polymorphisms in the IL-1 gene...
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