Article
-643C > T RANKL gene polymorphism is associated with osteoporosis in Tunisian postmenopausal women.
Climacteric : the journal of the International Menopause Society - 1 Aug 2017
Sassi R, Sahli H, Cheour E, Sellami S, El Gaaied A Ben Ammar
Abstract excerpt
OBJECTIVES: The dynamic nature of the skeleton is achieved by a remodeling process. Receptor activator of nuclear factor kappa B (RANK) ligand (RANKL) stimulates bone resorption by activating RANK signaling. Therefore it is considered as a candidate gene regulating susceptibility to osteoporosis. In the current study, we have investigated the association between the RANKL gene -693G > C and -643 C > T...
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