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Article

The RANKL/RANK/OPG signal trail: significance of genetic polymorphisms in the etiology of postmenopausal osteoporosis.

Ginekologia polska - 1 Jan 2016

Wolski Hubert, Drews Krzysztof, Bogacz Anna, Kamiński Adam, Barlik Magdalena, Bartkowiak-Wieczorek Joanna, Klejewski Andrzej, Ożarowski Marcin, Majchrzycki Marian, Seremak-Mrozikiewicz Agnieszka

Abstract excerpt

OBJECTIVES: Recent studies have demonstrated that disorders of bone metabolism, which is regulated by RANK/RANKL/OPG signaling pathway, are the cause of osteoporosis. The aim of the study was to investigate the distribution of genotypes of the RANK 575C>T and RANKL -643C>T polymorphisms and to analyze their relationship with bone parameters in postmenopausal women. MATERIAL AND METHODS: A total of 310...

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Identifiers

PMID: 27304650
DOI: 10.5603/GP.2016.0014

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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