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Article

Association of Polymorphisms in RANK and RANKL Genes with Osteopenia in Arab Postmenopausal Women.

Disease markers - 1 Jan 2020

Abdi Saba, Bukhari Ihtisham, Ansari Mohammed G A, BinBaz Rawan A, Mohammed Abdul Khader, Hussain Syed Danish, Aljohani Naji, Al-Daghri Nasser M

Abstract excerpt

The RANKL/RANK/OPG pathway regulates bone remodelling and turnover. However, the genetic background of bone mineral density (BMD) and osteopenia in Saudi postmenopausal women is yet to be studied. We studied the genetic polymorphism of RANKL/RANK/OPG with BMD and other associated factors in Saudi postmenopausal osteopenic women. A total of 439 (223 osteopenia and 216 control) postmenopausal women were recruited...

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Identifiers

PMID: 33376557
DOI: 10.1155/2020/1285216
PMCID: PMC7746462

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